Updated 16 July 2015

What's your diagnosis? – Case 19: lady who can't lose weight

Mrs L has trouble losing weight and feels tired all the time. Can you figure out what's wrong with her?


Mrs L is a 40 year old housewife with no medical history. She has tried every possible diet to lose weight, but she cannot stop gaining, despite all her efforts.

Over the past three months she has noticed that she feels tired for most of the day.

Winter is the worst time

She also experiences occasional headaches, is always sweaty and has also noticed occasional pain in her right wrist.

She recently had a bout of cold with flu-like symptoms, but thought it might be due to the fact that she doesn't dress warmly enough during the cold weather. Winter is the worst time for Mrs L as her skin tends to become very dry (although this doesn't only happen in winter); her hair also becomes dry and she is generally not in a good mood.

While she was waiting for the doctor, the nurse did her side-room tests:

Heart rate: 56 bpm

Blood pressure: 135/89 mmHg

Urine test: clear

Using the information above, what will be the most likely diagnosis, and what tests, if any, will the doctor consider to comfirm his suspicion?

What's your diagnosis? Join the guesswork on our Facebook page, or comment below.

NOTE: Health24's on-site GP Dr Owen Wiese will reveal new cases on Thursdays. We'll post the answer with the story on Mondays, or you can get it via the Daily Tip – sign up here.

Previously on What's Your Diagnosis?

What's your diagnosis? -  Case 1: vomiting and weight loss

What's your diagnosis? -  Case 2: eye pain

What's your diagnosis? -  Case 3: strange behaviour and a bullet in the back

What's your diagnosis? -  Case 4: seeing odd things

What's your diagnosis? - Case 5: mysterious lungs

What's your diagnosis? - Case 6: runner with seizures

What's your diagnosis? - Case 7: swollen knee

What's your diagnosis? - Case 8: bloody semen

What's your diagnosis? - Case 9: confusing neurological signs

What's your diagnosis? - Case 10: diabetic teenager with unusual signs and symptoms

What's your diagnosis? - Case 11: bruising with no apparent reason

What's your diagnosis? - Case 12: severe tummy pain

What's your diagnosis? - Case 13: severe sore throat

What's your diagnosis? - Case 14: abdominal pain and swelling

What's your diagnosis? - Case 15: the world is spinning

What's your diagnosis? - Case 16: numbness in forearm

What's your diagnosis? - Case 17: burning urine

What's your diagnosis? - Case 18: boy with persistent fever


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