US researchers studied 566 infants with a congenital heart defect (CHD) and 491 infants without a CHD, along with their parents.
They concluded that women who smoked from some point in the month before conception through to the end of their first trimester were 60 percent more likely to have babies with a CHD. This increased risk was still evident even if women took prenatal vitamins and limited their alcohol intake, and occurred regardless of age or race.
Exposure to second-hand smoke in early pregnancy also increased the risk of CHD, the study found.
Before you know you're pregnant"The heart's basic structures develop very early in pregnancy, before many women realize they are pregnant," study author Sadia Malik, an assistant professor of paediatrics at the University of Arkansas for Medical Sciences in Little Rock, explained in a prepared statement.
"Thus, even if a woman quits smoking at six weeks or later, her foetus will still have been exposed to the harmful effects of cigarette smoking during cardiac development," Malik said.
The findings were expected to be presented Tuesday at the American Heart Association's annual meeting, in Chicago.
Heart defects can range from holes between the chambers of the heart to the absence of one or more heart chambers or valves. – (HealthDayNews)
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November 2006