Five million babies have been born using assisted reproductive technologies such as in vitro fertilization since the late 1970s, according to a new study.
The first "test tube baby" was born in 1978, and by 1990 there had been about 90 000 such assisted births worldwide. That number grew to about 900 000 by 2000 and to more than 2.5 million by 2007.
Since 2007, about 2.4 million babies have been born via fertility treatments, according to the study, which is scheduled for presentation at the International Federation of Fertility Societies and American Society for Reproduction Medicine annual meeting in Boston.
"This comprehensive report confirms that we now have over 5 million babies born through assisted reproduction," IFFS board member Richard Kennedy said in a federation news release. "More than that, it shows that half of them have been born in the last six years. The number of babies born through [assisted reproductive technologies] is now about the same as the population of a US state such as Colorado, or a country such as Lebanon or Ireland. This is a great medical success story."
Another study presented at the meeting found that retrieving more than 15 eggs from a woman for use in fertility treatments leads to an increased risk of complications, but only a small increase in the likelihood of having a baby.
Researchers analysed more than 250 000 fertility treatment cycles performed in the United States from 2008 to 2010. They found that removing 16 to 20 eggs instead of 11 to 15 eggs increased the live birth rate from about 39% to nearly 43%, but raised the risk of a complication called ovarian hyperstimulation syndrome from 0.93% to 1.67%.
When more than 25 eggs were retrieved, the live birth rate was nearly 42%, while the risk of ovarian hyperstimulation syndrome rose to nearly 6.5%. The findings suggest that it may be necessary to re-evaluate the appropriate number of eggs to collect, the researchers said.
Because the research was presented at a medical meeting, it should be viewed as preliminary until published in a peer-reviewed journal.
The U.S. National Library of Medicine has more about in vitro fertilization.