20 June 2018

Dirty air in pregnancy may raise baby's blood pressure risk

According to a study, children exposed to high levels of 'fine-particulate air pollution' in late pregnancy were more likely to have high blood pressure.


Breathing polluted air is never wise for anyone, but pregnant women may pay an especially unwanted price, a new study found. 

"The findings from our study are another piece of evidence that air pollution exposure can affect your health and could affect your baby's health as well," said senior study author Noel Mueller.

Mueller's team found that children exposed to the highest levels of "fine-particulate air pollution" in late pregnancy were 61% more likely to have high blood pressure than those exposed to the least pollution.

He cautioned that this study cannot prove that air pollution is responsible for higher blood pressure in childhood, only that the two are associated.

Are you at risk?

"Pregnant women, however, should think about avoiding heavily trafficked areas as a way to avoid more air pollution exposures," said Mueller, an assistant professor of epidemiology at Johns Hopkins University Bloomberg School of Public Health in Baltimore.

Combustion from cars, oil, coal or wood can create tiny particles – 2.5 microns or less – called PM2.5. These can only be seen under a microscope. When inhaled, these particles can enter the circulatory system and lead to health problems, the researchers said in background notes.

In prior studies, direct exposure to PM2.5 has been tied to high blood pressure in children and adults. This type of air pollution also contributes to illness and premature death worldwide, Mueller said.

"We need regulations to keep our air clean, not only for the health of our planet, but also for the health of our children," Mueller said.

The report was published online in the Hypertension journal.

Early diagnosis and treatment key

The South African National Ambient Air Quality Standards are guidelines that regulate the amount of pollution in the air. The Waterberg-Bojanala Priority Area, Vaal Triangle Airshed Priority Area and the Highveld Priority Area are three areas in the country with the highest air pollution rates. 

"If maternal and early life pollution exposures increase the long-term risk of high blood pressure, then reducing early life pollution exposure through regulation and through local and regional efforts may help protect children from having higher blood pressure in childhood," said Dr Diane Gold, a pulmonologist and professor of medicine.

This might then "improve their long-term cardiovascular and cerebrovascular health," she added, referring to the link between high blood pressure and stroke.

There are often no symptoms of high blood pressure in children or adults. Early diagnosis and treatment are key, according to the American Heart Association. Lifestyle changes, such as a healthy diet, weight management and exercise, are usually recommended. Medication may also be prescribed.

Sharp rise in odds

For the study, Mueller and colleagues collected data on nearly 1 300 mother-child pairs who took part in the Boston Birth Cohort study.

Children's blood pressure was measured at "well child" visits when they were three to nine years old.

Systolic blood pressure (top number in a blood pressure reading) in the highest 10% was considered elevated.

To gauge exposure to air pollution, Mueller's group matched EPA data to each woman's home address.

Specifically, the researchers looked for concentrations of PM2.5.

Exposure to high levels of fine particulate matter in the third trimester was associated with a sharp rise in odds for high blood pressure in childhood, according to the study.

Worse for the poor

The researchers said they accounted for other factors that influence child blood pressure, such as birth weight and whether the mother smoked.

They also determined that women's exposure to PM2.5 before pregnancy was not associated with blood pressure in their children. This is evidence that exposure in the womb is linked to childhood blood pressure, Mueller said.

Gold, co-author of an editorial accompanying the study, said the dangers of air pollution may be worse for the poor.

"Exposures to pollution may be higher in disadvantaged communities, and may ultimately contribute to health disparities," she said.

In 2016, World Bank statistics determined that 20 000 people die from air pollution in South Africa per year. Hartebeespoort was identified as the city with the highest pollution rates in the country, with Tshwane and Johannesburg following closely behind.

Image credit: iStock 




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