15 September 2014

French company implants second artificial heart

French media reported that doctors had implanted an artificial heart made by the Carmat company for a second time.


French company Carmat has confirmed that it fitted a second patient with one of its artificial hearts and would continue its clinical trials on two more patients.

Permanent implant

Carmat's device, which mimics nature's work using biological materials and sensors, is designed to serve not as a bridge to a heart transplant but as a permanent implant, extending life for terminally ill patients who cannot hope for a real organ, because they are too old or donors are scarce.

Shares in Carmat rose as much as 19 percent after French media reported that doctors had implanted an artificial heart made by the company for a second time.

Read: Docs save baby with artificial heart

The clinical trial will be considered a success if Carmat's first patients survive with the implant for at least a month. The patients selected suffer from terminal heart failure – when the sick heart can no longer pump enough blood to sustain the body – and have only a few weeks, or even days, to live.

Carmat said it does not plan to publish any information on the results of this feasibility study until it is completed.

Bovine tissue

If the results of these first safety tests are positive, Carmat has said it would fit the device into about 20 patients with less severe heart failure, with an aim to request the right to market its device in Europe by 2015.

Patient enrolment had been put on hold in March after the first person to be implanted with the device, a 76-year-old man, died two and a half months after his operation.

Read: Artificial hearts will make up for lack of human ones

Carmat's device, developed by a team of engineers from Airbus parent company EADS, weighs about 900g (around 2 lb) – nearly three times more than an average healthy human heart. It mimics heart muscle contractions and contains sensors that adapt the blood flow to the patient's moves.

It is powered by external, wearable lithium-ion batteries. Inside the heart, surfaces that come into contact with human blood are made partly from bovine tissue instead of synthetic materials such as plastic that can cause blood clots.

Among Carmat's competitors for artificial heart implants are privately-held SynCardia Systems and Abiomed, both of the United States.

Read more:

Airplane technology for heart
Landmark surgery in SA
Smallest heart pump implanted

Image: Artificial human heart from Shutterstock

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