Risperdal was always going to be a big gamble.Tofranil is an anti-depressant that has been used for many years to treat enuresis/bed wetting in children over 5 years of age.It is regarded as a safe treatment but the dose has to be carefully monitored. I have no experience of the use of Tofranil in children with ODD. It is certainly a safer medicine than Risperdal, but if Tofranil is used the important rule for this kind of medication is vital: 'start low,go slow and monitor regularly' This means start with a low dose;only increase the dose by small amounts at a time if necessary;your son will need follow up by the psychiatrist.
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