Your question only came up on the Paediatrician's question today (6 May)
The most likely cause of swelling and tingling of your thumb is an infection. Based on your description of noticing a small pustule with a dark spot in the centre, the most likely possibility is a splinter or possibly a prick due to a thorn such as a rose thorn. Infection is the most likely cause, but another less likely cause is that this is due to gout. Gout can start for the first time in the thumbs although the big toe is more likely. If your thumb is still swollen and painful, you must see a doctor. If this is due to infection, you will need an antibiotic.
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