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Tuberculosis

22 July 2011

Stopping the spread of TB in HIV+

Preventive therapy using the antibiotic isoniazid significantly reduces the incidence of tuberculosis and death when widely used in public HIV clinics.

Preventive therapy using the antibiotic isoniazid significantly reduces the incidence of tuberculosis and death when widely used in public HIV clinics, an international effort led by physician-scientists at Rio de Janeiro Municipal Health Secretariat, Brazil, and the Johns Hopkins University in the United States, and funded by The Consortium to Respond Effectively to the AIDS/TB Epidemic (CREATE) reported.

The investigators used a "phased implementation" design for the intervention study, meaning that clinics received training in the use of IPT in a sequential fashion, with all clinics eventually being included. Rates of TB were compared in clinics before and after the intervention.

 

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