Jaundice is the term used to describe the yellow appearance of skin and membranes due to the deposition of bilirubin, which is toxic substance.
Because of the complexity of the BR metabolism, it is clinically convenient to classify disorders into two major groups according to the predominant type of BR in the serum.
Predominantly CBR, due to liver cell disease, problems with liver excretion at cell level, or obstruction to the bile duct system.
Problems outside the liver tissue – mainly obstructions
- Strictures after surgery or other procedures
- Parasitic infection, like liver flukes and roundworms
- Stones in the bile ducts