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Stop-smoking

26 August 2010

Nicotine fuels breast cancer

Nicotine may directly promote the development of breast cancer by binding to a certain cell receptor, says a new study.

Nicotine may directly promote the development of breast cancer by binding to a certain cell receptor, says a new study.

The researchers found that breast cancer cells consistently overproduced the alpha 9 subunit of nAChR (a9-nAChR), and that production of this subunit was higher in advanced-stage breast cancer than in early-stage cancer.

They then conducted laboratory tests that showed reducing levels of a9-nAChR inhibited tumour growth, while increasing levels of the subunit or treating more normal breast cells with nicotine led to the development of cancer characteristics.

 

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