Tiotropium is the active ingredient of Spiriva capsules for
inhalation (Nappi code: 702523-006) and Spiriva capsules for inhalation (Nappi
Tiotropium is a bronchodilator. Bronchodilators are drugs that relax the
muscles around the airways, helping the airways to open up, so making it easier
In South Africa tiotropium is registered for the long-term treatment of
chronic obstructive pulmonary disease including chronic bronchitis and
Tiotropium takes longer to start working compared to some other
bronchodilators (its effects last longer than that of most of the others,
though). Because of this, tiotropium is not the ideal drug for treating acute
asthma attacks - instead, it should be used regularly each day to keep the
airways open and help prevent breathing difficulties.
How does tiotropium work?
Tiotropium blocks the effect of a chemical called acetylcholine, which causes
narrowing of the airways. By doing this, the muscle around the airways relaxes
and the airways open up, making breathing easier.
Drug schedule: schedule 3
Available as: tiotropium is available as inhalation capsules.
What does it do? Tiotropium widens/opens the airways to make breathing
Overdose risk: low
Dependence risk: low
Is tiotropium available as a generic? no
Is tiotropium available on prescription only? yes
Onset of effect: within 5 minutes
Duration of action: up to 24 hours
Stopping this medicine: do not stop treatment with this drug without
consulting your doctor. The original symptoms may recur.
Consult your doctor before using this drug if:
- you have glaucoma
- you have an enlarged prostate
- you have been diagnosed with bladder neck obstruction
- you have a kidney disorder
Pregnancy: avoid. It is unknown how this medication may affect your
baby. Consult your doctor before using this drug, or if you are planning to fall
Breastfeeding: avoid. It is unknown how this medication may affect
your baby. Consult your doctor before use.
Porphyria: avoid. It is unknown how this medication may affect your
condition. Consult your doctor before use.
Infants and children: this medication is not intended for use in
children under the age of 18 years.
The elderly: o special precautions need to be taken.
Driving and hazardous work: no special precautions need to be
Alcohol: no special precautions need to be taken.
Possible side effects
| Side effect
|| Consult your doctor
|| Only if severe
|| In all cases |
||possible increase in tiotropium's side effects |
||possible increase in tiotropium's side effects|
A small overdose is no cause for concern. In case of intentional large
overdose, seek emergency medical attention.
Adults: one capsule for inhalation once daily, at the same time each day.
This material is not intended to substitute medical advice, but is for
informational purposes only.
Please consult a physician for specific treatment and