Meds and you

27 September 2013

Mometasone nasal spray

Mometasone is an intranasal corticosteroid.


Mometasone is the active ingredient of Nasonex nasal spray (Nappi code: 883253-004).

General information

Mometasone is an intranasal corticosteroid. Intranasal corticosteroids are steroid medicines that are formulated for use as a nasal spray to decrease inflammation in the nasal passages. Symptoms of allergic rhinitis such as a runny, itchy or blocked nose and sneezing are a result of inflammation in the nasal passages.

In South Africa mometasone is registered for the treatment and prevention of seasonal and perennial allergic rhinitis, including hay fever.

High doses of this medicine for prolonged periods of time may increase systemic absorption, which may lead to a various adverse effects. Systemic effects are however unlikely at the recommended dose.

Note that this nasal spray will not relieve the symptoms of nasal allergies immediately - it may take several days of treatment to achieve its maximum benefit. To achieve its full effect, the spray should be used regularly throughout the allergic period to keep the nasal inflammation under control.

How does mometasone work?

Mometasone as a nasal preparation reduces nasal symptoms by reducing inflammation and mucus production in the nose.

Fast facts

Drug schedule: schedule 3

Available as: mometasone is available as an aqueous nasal spray.

What does it do? Mometasone decreases inflammation in the nasal passages.

Overdose risk: low

Dependence risk: low

Is mometasone available as a generic? no

Is mometasone available on prescription only? yes

User information

Onset of effect: within 3 days

Duration of action: several days after stopping treatment

Special precautions

Consult your doctor before using this drug if:

- you have bleeding tendencies, or suffer from recurring nasal bleeding

- you have a viral, bacterial or fungal nasal or respiratory infection

- you are also taking oral corticosteroid drugs

Pregnancy: avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.

Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.

Porphyria: avoid. It is unknown how this medication may affect your condition. Consult your doctor before use.

Infants and children: this medication is not intended for use in children under the age of 2 years.

The elderly: no special precautions need to be taken.

Driving and hazardous work: no special precautions need to be taken.

Alcohol: no special precautions need to be taken.

Possible side effects

Side effect Frequency
Consult your doctor



Only if severe In all cases
Burning x
Stinging x
Sneezing x
Nasal dryness x
Headache x
x x
x x


Drug interactions

Interactions are unlikely when this medication is used as directed.

Overdose action

A small overdose is no cause for concern. In case of intentional large overdose, seek emergency medical attention.

Recommended dosage

Use once daily in each nostril.

This material is not intended to substitute medical advice, but is for informational purposes only.

Please consult a physician for specific treatment and recommendations.


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