Miconazole is the active ingredient of Dermax (Nappi Code: 707299-001),
Lamisil Tabs (Nappi Code: 842087-001 & 792713-001), Merck-Terbinafine (Nappi
Code: 705114-001), Nafin 250 (Nappi Code: 706553-001), Terbane (Nappi Code:
706757-001), Terbicil (Nappi Code: 705430-001), Lamisil cream (Nappi Code:
792705- 017/009), Lamisil spray (Nappi Code: 703033-001 & , 836486), Lamisil
Dermgel (Nappi Code: 880892-005) and Terbicil Cream (Nappi Code: 706073-
Miconazole is also one of multiple active ingredients found in Daktacort
(Nappi Code: 717266-001).
Miconazole is an antimycotic. Antimycotics are
drugs that destroy or prevent the growth of fungi. An antimycotic drug is thus
an antifungal drug.
In South Africa miconazole is registered for the treatment of fungal
infections of the mouth, throat and skin.
Miconazole oral gel can also be taken to treat fungal infections of the
stomach or intestines.
Systemic absorption of miconazole after topical application is very low, but
caution is still advised in patients being treated with warfarin (see
Although miconazole also has some antibacterial action, it is only effective
in treating topical fungal infections and will not be effective in treating
Treatment with miconazole should be continued for two days after the symptoms
have cleared up to ensure the infection is fully treated and thus help prevent
it coming back.
How does miconazole work?
Miconazole inhibits the manufacturing of
substances vital for fungal membrane stability and cell development.
Drug schedule: schedule 2, 4
Available as: miconazole is
available as topical, vaginal and oral applications.
What does it do?
Miconazole destroys or prevents the growth of fungi.
Dependence risk: low
Is Miconazole available as a
Is Miconazole available on prescription only? yes
Onset of effect: up to 3 days
Duration of action: up to 12
Stopping this medicine: Do not stop taking miconazole without
consulting your doctor. If you stop taking this medicine too soon, your symptoms
Consult your doctor before using this drug
- you have a liver disease
- you have porphyria
- you are taking other antifungal medication
Pregnancy: avoid. It is unknown how this medication may affect your
baby. Consult your doctor before using this drug, or if you are planning to fall
Breastfeeding: avoid. It is unknown how this medication may
affect your baby. Consult your doctor before use.
This medication may cause serious adverse effects. Consult your doctor before
Infants and children: a reduced dose of the oral gel is needed in
The elderly: no special precautions need to be
Driving and hazardous work: no special precautions need to be
Alcohol: no special precautions need to be taken.
Possible side effects
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Consult your doctor
Only if severe
In all cases
|gliclazide, glibenclamide, tolbutamide
||blood sugar may fall to dangerously low levels|
||risk of phenytoin toxicity|
||life-threatening heart rhythm disturbances may develop|
||risk of bleeding|
Consult your doctor before using this drug if
you have a liver disease or if you have porphyria.
A small overdose is no cause for concern. In case
of intentional large overdose seek emergency medical attention.
This material is not intended to substitute medical advice, but is
for informational purposes only. Please consult a physician for specific
treatment and recommendations.