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Meds and you

27 September 2013

Meprobamate

Meprobamate is effective in treating the symptoms of anxiety and tension. In South-Africa meprobamate is commonly found as an ingredient of higher schedule painkillers.

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Meprobamate is the active ingredient of Equanil (NAPPI code: 723894-019).

Meprobamate is also one of multiple active ingredients found in Adco-Payne (NAPPI code: 894282-006), Antipyn Forte (NAPPI code: 786780-010/029 ), Ban Pain (NAPPI code: 787671-010), Fevapar (NAPPI code: 700834-001), Go-Pain (NAPPI code: 823538-001/003), Medipyn T, Megapyn (NAPPI code: 782874-029), Meprogesic (NAPPI code: 741957-124), Mepromol (NAPPI code: 786802-014), Micro-Gesic (NAPPI code: 701746-003), Painagon (NAPPI code: 752177-001/036 ), Salterpyn (NAPPI code: 809055-007), Spectrapain Forte (NAPPI code: 765643-006/14/22, 834440-008/024 & 765643-022 ), Stilpane (NAPPI code: 766828-018/026 & 766798-003 ), Stopayne (NAPPI code: 766925-005 & 766933-008 ), Supragesic (NAPPI code: 767816-005), Synaleve (NAPPI code: 768375-010 ), Tenston (NAPPI code: 769649-009/017/025 & 769657-001/028/036), Trinagesic (NAPPI code: 708658-016) and Vacudol (NAPPI code: 797529-004) .

General information
Meprobamate is effective in treating the symptoms of anxiety and tension. In South-Africa meprobamate is commonly found as an ingredient of higher schedule painkillers, mainly due to its effectiveness in treating tension-related pain.

Meprobamate can be habit-forming and should only be taken as directed by your doctor, and only for as long as recommended.

Treatment should also not be stopped abruptly, especially if you have been taking this drug for a prolonged period of time. To prevent withdrawal symptoms, you should decrease your dose gradually only as directed by your doctor.

Meprobamate may interact with commonly available over-the-counter cold and flu medication. You should consult your doctor or pharmacist before starting any new medication.

How does meprobamate work?
Meprobamate affects levels of chemicals in your brain, thereby reducing anxiety and tension.

Fast facts

Drug schedule: schedule 5
Available as: meprobamate is available as tablets
What does it do? Meprobamate has a relaxing effect. It reduces anxiety and disorders that may result as a result of tension, including muscle spasms.
Overdose risk: high
Dependence risk: high
Is meprobamate available as a generic? no
Is meprobamate available on prescription only? yes

User information

Dietary advice: if stomach irritation occurs meprobamate should be taken with food or milk.
Stopping this medicine: treatment should not be stopped abruptly as it may cause a return of pre-existing symptoms. Your dose needs to be gradually decreased under the supervision of your doctor.
Prolonged use: the effectiveness of Meprobamate over prolonged periods of time - periods of more than three months - has not been proven. Tolerance may develop to this medication making it less effective with prolonged use. Your doctor should periodically review your treatment and the need to continue with this drug.

Special precautions
Consult your doctor before using this drug if:

  • you have a kidney or liver disease

  • you are epileptic

  • you have a respiratory disorder

  • you have a history of alcohol or substance abuse

Pregnancy: avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.
Breastfeeding: avoid. This medication is passed through breast milk and may affect your baby adversely. Consult your doctor before use.
Porphyria: avoid. It is unknown how this medication may affect your condition. Consult your doctor before use.
Infants and children: this medication is not intended for use in children under the age of six.
The elderly: caution is advised in the elderly, as adverse effects may occur more frequently.
Driving and hazardous work: caution is advised as use of this medication may lead to dizziness, light-headedness and/or sedation. Avoid such activities until you know how this medication affects you.
Alcohol: avoid concomitant use of alcohol with this medication as it may cause drowsiness.

Possible side effects

Side Effect
Frequency
Consult your doctor

Common
Rare
Only if severe
In all cases
drowsiness, dizziness
X

X

headache
X

X

slurred speech

X

X
weakness

X

X
visual impairment

X
X

nausea,vomitting

X
X

diarrhoea
X

X

fast, irregular heart rate

X

X
bruising/bleeding

X

X
swelling

X

X
skin rash

X

X
chills/fever

X

X
difficulty breathing

X

X

Interactions

Drug interactions

alcohol (and other suppressants of the CNS) enhanced CNS effects i.e. sedation
oral contraceptives risk of potential contraceptive failure. An alternative method of contraception is advised

Overdose action
An overdose of this medication can be fatal. Seek immediate emergency medical attention.

Recommended dosage
Adults: Up to 400 mg 3 times daily. Daily dose should not exceed 2400 g.

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.
 
 

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