Meds and you

Updated 11 February 2013


Lansoprazole is prescribed to treat ulcers of the stomach and duodenum, the first part of the small intestine that connects to the stomach.


Lansoprazole is the active ingredient of Adco-Roznal, Aspen Lansoprazole, Lancap, Lansoloc, Lanzor, Ran-Lansoprazole and Simayla Lanzoprazole.

General information

Lansoprazole is prescribed to treat ulcers of the stomach and duodenum, the first part of the small intestine that connects to the stomach. It is also effective in treating gastro oesophageal reflux, the backward flow of stomach acid contents into the oesophagus, the tube that connects the mouth to the stomach.

It is prescribed for longer periods of time to treat patients with Zollinger-Ellison syndrome, a rare condition associated with a tumour that creates high levels of stomach acid secretion.

In some cases lansoprazole is prescribed along with other medication - often two different antibiotics - to eradicate H. Pylori, a cause of stomach ulcers.

For this drug to remain effective has to be taken regularly; an ulcer may recur when you stop treatment prematurely.

Lansoprazole can mask the symptoms and may delay the diagnosis of stomach cancers -possible malignancy should be excluded prior to start of treatment.

How does lansoprazole work?

This medication decrease the production of acid in the stomach as a result of blocking an enzyme needed for acid manufacture.

Fast facts

Drug schedule: schedule 4

Available as: lansoprazole is available as capsules

What does it do ? lansoprazole reduce stomach acid production

Overdose risk : low

Dependence risk: low

Is Lansoprazole available as a generic? yes

Is Lansoprazole available on prescription only? yes

User information

Onset of effect: within 3 hours

Duration of action: up to 24 hours

Dietary advice: lansoprazole should best be taken 30 minutes before a meal; avoid food that may increase the production of stomach acid, such as alcohol, spicy meals, and so forth.

Stopping this medicine: do not discontinue using this medication without consulting your prescriber as symptoms may recur with premature discontinuation

Prolonged use: Although few problems are expected, lansoprazole is not intended for indefinite use.

Special precautions

Consult your doctor before using this drug if:

  • you have a liver disease
  • you are taking any other medication

Pregnancy: avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.

Breastfeeding: avoid. This medication is passed through breast milk and may affect your baby adversely. Consult your doctor before use.

Porphyria: avoid. This medication may cause serious adverse effects. Consult your doctor before use.

Infants and children: This medication is not intended for use in children and should only be prescribed by a paediatrician.

The elderly: no special precautions need to be taken.

Driving and hazardous work: caution is advised as use of this medication may lead to dizziness and/or light-headedness. Avoid such activities until you know how this medication affects you.

Alcohol: avoid concomitant use of alcohol with this medication as it may aggravate your condition and reduce the apparent efficacy of this medication

Possible side effects:

Side effect


Consult your doctor



Only if severe

In all cases







nausea/ vomiting






skin rash



unexplained bruising







Drug interactions:


may reduce effect of lansoprazole; should be taken at least 1 hour apart


may reduce effect of lansoprazole; should be taken at least 1 hour apart


risk of warfarin toxicity

ketoconazole; itraconazole

reduced effect of these anti-fungal drugs

oral contraceptives

risk of increased side-effects


risk of phenytoin toxicity


risk of theophylline toxicity

Disease interactions

Consult your doctor before using this drug if you have a liver disease

Overdose action

A small overdose is no cause for concern. In case of intentional large overdose seek emergency medical attention.

Recommended dosage

Adults: 15-30 mg once daily.

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.


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