Ipratropium bromide is the active ingredient of Adco-Ipratropium Bromide
inhalation solution (Nappi code: 890164-007, 89172-003), Atrovent unit dose
vials (Nappi code: 794007-007, 786241-004), Atrovent HFA metered dose inhaler
(Nappi code: 706543-001), Atrovent inhalation solution (Nappi code: 835633-004)
& Ipvent-40 metered dose inhaler (Nappi code: 704681-001).
Ipratropium bromide is a broncho-dilator. Broncho-dilators are drugs that
relax the muscles around the airways, helping the airways to open up, so making
it easier to breathe.
In South Africa ipratropium bromide is registered for the treatment of
broncho-spasm in chronic bronchitis, and asthma.
Ipratropium bromide takes longer to start working compared to some other
broncho-dilators (its effects last longer than that of most of the others,
though). Because of this, ipratropium alone is not the ideal drug for treating
acute asthma attacks and it's often combined with other faster-acting drugs.
How does ipratropium bromide work?
Ipratropium blocks the effect of a chemical called acetylcholine, which
causes narrowing of the airways. By doing this, the muscle around the airways
relaxes and the airways open up, making breathing easier.
Drug schedule: schedule 3
Available as: ipratropium bromide is available as unit-dose vials, a
solution for inhalation, and a metered-dose inhaler
What does it do? Ipratropium bromide widens/opens the airways to make
Overdose risk: low
Dependence risk: low
Is ipratropium bromide available as a generic? yes
Is ipratropium bromide available on prescription only? yes
Onset of effect: within 15 minutes
Duration of action: up to 8 hours
Consult your doctor before using this drug if:
- you have glaucoma
- you have an enlarged prostate
- you have been diagnosed with bladder neck obstruction
- you have cystic fibrosis
Pregnancy: avoid. It is unknown how this medication may affect your
baby. Consult your doctor before using this drug, or if you are planning to fall
Breastfeeding: avoid. It is unknown how this medication may affect
your baby. Consult your doctor before use.
Porphyria: avoid. It is unknown how this medication may affect your
condition. Consult your doctor before use.
Infants and children: this medication is not intended for use in
children under the age of 6 years.
The elderly: no special precautions need to be taken.
Driving and hazardous work: no special precautions need to be
Alcohol: no special precautions need to be taken.
Possible side effects
||Call your doctor
||Only if severe
||In all cases|
No significant interactions known.
A small overdose is no cause for concern. In case of intentional large
overdose, seek emergency medical attention.
Adults: Use 3 - 4 times daily, as directed.
This material is not intended to substitute medical advice, but is for
informational purposes only.
Please consult a physician for specific treatment and