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Meds and you

Updated 11 February 2013

Flurbiprofen

Flurbiprofen is a non-steroidal anti-inflammatory medication. It is prescribed to relieve inflammation, swelling, stiffness and is an effective pain killer.

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Flurbiprofen is the active ingredient of Transact patches.

General Information

Flurbiprofen is a non-steroidal anti-inflammatory medication. It is prescribed to relieve inflammation, swelling, stiffness and is an effective pain killer. It is of particular use in arthritic conditions and trauma.

This medication does not cure the underlying condition responsible for pain or inflammation, but simply keeps the symptoms under control.

How does flurbiprofen work?

Flurbiprofen blocks the production of chemicals in the body responsible for pain, swelling and inflammation.

Fast facts

Drug schedule: Schedule 2

Available as: Flurbiprofen is available as local-acting patch.

What does it do? Flurbiprofen reduces pain, and inflammation.

Overdose risk: Low

Dependence risk: Low

Is flurbiprofen available as a generic ? No

Is flurbiprofen available on prescription only? No

User information

Onset of effect: Within 60 minutes

Duration of action: Up to 12 hours

Stopping this medicine: Flurbiprofen patches can be safely discontinued when no longer needed.

Prolonged use: The likelihood of adverse effects increases with prolonged use.

Special precautions

Consult your doctor before using this drug if:

  • You have asthma
  • You have kidney or liver disease
  • You have a bleeding disorder
  • You have heart disease
  • You are taking blood thinning medication
  • You are allergic to aspirin or any other medication
  • You are taking other medication.

Pregnancy: Avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.

Breastfeeding: Avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.

Porphyria: This medication is safe to use.

Possible side effects

Side effect

Frequency

Consult your doctor

Common

Rare

Only if severe

In all cases

Local irritation

x

Rash/itch

x

x

Interactions:

Drug interactions:

Although rare, systemic absorption of this drug may have the following interactions:

Blood pressure medication

Reduced pressure lowering effect

Alcohol

Potential gastrointestinal symptoms

Warfarin

Risk of bleeding

Asthma medication

Reduced effect of asthma medication; risk of asthma attack

Cardiac glycosides, digoxin

Risk that heart failure may be more severe.

Corticosteroids

Potential gastrointestinal symptoms

Ciclosporin

Potential flurbiprofen toxicity

Methotrexate

Potential methotrexate toxicity

Diuretics

Potential risk of kidney damage

Blood glucose lowering drugs

Risk of prolonged low blood sugar

Baclofen

Potential baclofen toxicity

Other NSAID's

Potential risk of gastrointestinal bleeding

Probenecid

Risk of flurbiprofen toxicity

Quionolone antibiotics

Risk of seizures

Tacrolimus

Increased risk of kidney damage

Zidovudine

Increased risk of zidovudine toxicity

Disease interactions

Consult your doctor before using this drug if you have asthma, a stomach ulcer, bleeding disorder, you are taking blood thinning medication, or if you are allergic to aspirin or any other medication.

Recommended dosage

Adults: Apply one patch to the affected area every 12 hours.

 

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