Clobetasol is the active ingredient of Clobex shampoo (Nappi code:
710464-001), Dermovate cream (Nappi code: 718718-003), Dermovate scalp
application (Nappi code: 824216-008), Dermovate ointment (Nappi code:
718726-006), Dovate cream (Nappi code: 807249-009), Dovate ointment (Nappi code:
807230-006), Xenovate cream (Nappi code: 868299-006) and Xenovate ointment
(Nappi code: 868302-007).
Clobetasol is a topical corticosteroid. Topical corticosteroids are drugs
that that are formulated for use on the skin. They reduce inflammation and are
effective for treating inflammatory skin conditions.
In South Africa clobetasol is registered for the treatment of psoriasis;
eczema; steroid responsive dermatosis, and scalp psoriasis.
Clobetasol is considered to be one of the strongest topical corticosteroids
available and should therefore only be used in the treatment of conditions that
did not respond to other topical steroids.
This medication should be applied sparingly and as a thin layer to the
affected area of the skin. Do not apply to broken skin, or apply more of the
medication than directed. Misuse of this medicine may lead to thinning of the
skin, or when systemically absorbed, a decrease in the production of natural
hormones by the adrenal glands.
Speak to your doctor before applying this medicine to infected skin.
How does clobetasol work?
When applied to the skin, clobetasol reduces the release of inflammatory
chemicals. This reduces inflammation and its associated symptoms.
Drug schedule: schedule 4
Available as: slobetasol is available as cream, ointment, scalp
application and shampoo.
What does it do? Clobetasol relieves inflammation of the skin.
Overdose risk: low
Dependence risk: low
Is clobetasol available as a generic? yes
Is clobetasol available on prescription only? yes
Onset of effect: within 12 hours
Duration of action: up to 24 hours
Stopping this medicine: do not stop using this medication abruptly as
it may cause a recurrence of the original symptoms being treated. Consult your
doctor prior to discontinuing treatment.
Prolonged use: this medicine is generally not used for longer than 4
Consult your doctor before using this drug if:
- you have a bacterial, fungal or viral skin infection
- you have porphyria
- you have skin ulcers
- you have acne, or rosacea
Pregnancy: avoid. It is unknown how this medication may affect your
baby. Consult your doctor before using this drug, or if you are planning to fall
Breastfeeding: avoid. It is unknown how this medication may affect
your baby. Consult your doctor before use.
Porphyria: avoid. This medication may cause serious adverse effects.
Consult your doctor before use.
Infants and children: this medication is not intended for use in
children under the age of 1 year. Shampoo only for use in adults.
The elderly: no special precautions need to be taken.
Driving and hazardous work: no special precautions need to be
Alcohol: no special precautions need to be taken.
Possible side effects
||Consult your doctor
||Only if severe
||In all cases|
Interactions are uncommon when this medication is used as directed
A small overdose is no cause for concern. In case of intentional large
overdose, seek emergency medical attention.
Apply sparingly to the affected area 1 - 2 times daily.
This material is not intended to substitute medical advice, but is for
informational purposes only.
Please consult a physician for specific treatment and