Heart Health

20 October 2016

Atrial fibrillation doesn't always require blood thinners

A new study suggests that patients with only short episodes of atrial fibrillation aren't at enough risk for a stroke to warrant blood thinners.


People with an abnormal heart rhythm called atrial fibrillation typically take powerful blood thinners to prevent strokes. But, some patients who have implanted pacemakers or defibrillators may not always need the drugs, a new study suggests.

Only a few seconds

Those who suffered only short bouts of atrial fibrillation – estimated at 20 seconds or less – were at no more risk for stroke or other heart complications than people without atrial fibrillation, the researchers found.

"Some patients have atrial fibrillation 100 percent of the time, while others might have only a few seconds of atrial fibrillation once a year," explained study author Dr Steven Swiryn. He's a clinical professor of cardiology at the Feinberg School of Medicine at Northwestern University in Chicago.

"Where atrial fibrillation only happens rarely and lasts a short time, it can be difficult to detect," Swiryn said.

Implanted devices such as pacemakers and defibrillators monitor a patient's heart rhythm constantly, and they can spot short episodes of atrial fibrillation, he said.

Read: Implantable defibrillator works without touching heart

"We can then more accurately answer the question, 'How much atrial fibrillation does the patient have to have in order to be at risk of stroke and benefit from anticoagulation [blood thinners]?'" Swiryn said.

Other contributing factors

The answer seems to be that patients with only short episodes of atrial fibrillation aren't at enough risk for a stroke to warrant blood thinners, he said.

"This allows physicians to avoid prescribing anticoagulation unnecessarily, since the risk of bleeding may be more than the benefit of stroke prevention," Swiryn said.

One heart expert agreed.

"Short episodes of atrial fibrillation that typically last 15 to 20 seconds are really low risk and that should not trigger the use of anticoagulants," said Dr Nicholas Skipitaris, director of cardiac electrophysiology at Lenox Hill Hospital in New York City.

Read: Atrial fibrillation (AF) increases stroke risk

But starting a patient on a blood thinner also depends on several factors, not just the length of episodes of atrial fibrillation, Skipitaris added. These include the patient's age, gender and whether they have other conditions such as heart failure, high blood pressure or diabetes.

An ongoing study

And another heart expert added another caveat.

"More frequent episodes, of even short duration, of atrial fibrillation might still be a concerning development," said Dr David Friedman. He is chief of heart failure services at Northwell Health Long Island Jewish Valley Stream Hospital in Valley Stream, New York.

"Much in the same way as one high blood pressure reading does not automatically mean someone has hypertension, the decision needs to be sorted out with trends over a period of time," he added.

Atrial fibrillation is the most common abnormal heart rhythm condition, and affects about 2.7 million Americans. People who have prolonged episodes of atrial fibrillation have an increased risk for heart complications and stroke. Guidelines recommend that patients with atrial fibrillation take blood thinners to reduce their stroke risk, Swiryn said.

Read: Atrial fibrillation requires lifestyle changes

For the study, Swiryn and his colleagues looked at 37,000 EKGs – a test that graphs heart rhythms – from more than 5,000 patients over two years. All the participants took part in the RATE Registry, an ongoing study that follows patients with pacemakers or defibrillators.

While those with long episodes of atrial fibrillation were more likely to be hospitalised or die than those without the condition, those with short episodes were not, the study found.

The report was published in the journal Circulation.

Read more:

Healthy lifestyle key to easing atrial fibrillation

Smartphone-synced device detects irregular heartbeat

Cape Town leader in cryo-balloon atrial fibrillation therapy


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