IGF-1 is released by the liver and is similar in molecular structure to insulin. The researchers said the hormone plays an important role in childhood growth and continues to have an effect in adulthood, United Press International reported.
At the start of the study, serum samples were taken from 376 healthy men, ages 73 to 94. The men were followed for up to eight years.
Men with the lowest level of IGF-1 activity had a significantly higher death rate than those with the highest level of activity.
The researchers said the results were especially significant in people at high risk of death from cardiovascular complications, UPI reported. The study was published in The Journal of Clinical Endocrinology and Metabolism. – (HealthDay News, May 2008)
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