People with migraines either with or without an aura preceding the headache show changes in the structure of their brains on imaging tests, researchers say.
"The clinical significance of these changes is unclear," said senior study author Dr Messoud Ashina, an associate professor and director of the human migraine research program at the Danish Headache Center and Glostrup Hospital, in Copenhagen. "It is not clear how and why these lesions develop, what they are and what long-term consequences they have for individuals with migraine. Therefore, I do not think the patient should be concerned, but treatment and control of migraine is recommended," he added.
The review found that people who had migraines were more likely to have changes in their brains than were people who didn't have migraines. Those who had migraines with auras appeared to be more likely to have these changes than those who had migraines with no auras, but the association wasn't found to be statistically significant, according to Ashina.
Although the study found an increased risk for certain brain changes among people who have migraines, it did not establish a cause-and-effect relationship.