11 November 2010

Gene Mutations Seem to Make a Leukemia More Deadly

Study found patients with acute myeloid leukemia who had the variant were more likely to die quickly

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"We have to know the gene before we can design the targeted therapy, and we need to understand the mechanism," explained study senior author Dr. Timothy Ley, a professor of medicine and genetics at Washington University in St. Louis. "The mutations provide a new clue to find out how the mechanism might affect gene regulation in patients with these mutations. Hopefully, [additional studies] will tell us a lot more about how to think about reversing effects of mutations in patients with this disease."


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