18 June 2007

Insulin weight loss can kill

Some diabetics are cutting down on insulin in order to lose weight, a practice that can be fatal, experts say.

Like many teenage girls, Lee Ann Thill was obsessed with her appearance. A diabetic, she was already suffering from bulimia - forcing herself to throw up to lose weight. But it was not enough, and she had recently put on 9 kilograms.

Then one day at a camp for diabetic teens, she heard counsellors scold two girls for practising "diabulimia" - not taking their insulin so they could lose weight.

Do you not realise you could die if you skip your insulin? the counsellor scolded.

But Thill, who has Type 1, or juvenile diabetes, focused on this: skipping insulin equals weight loss. For the next 17 years, diabulimia was her compulsion.

Just enough to function
"I took just enough insulin to function," said Thill, now 34.

Today, she worries about the long-term damage that may have come from her weight obsession. At 25, a blood vessel haemorrhage in her eye required surgery. At 28, doctors told her she had damaged kidneys.

"I'm fearful for the future," Thill said. "I feel very strongly that had I taken care of myself, I could have lived as long as anyone without diabetes. I don't think that's going to happen now."

Diabulimia is usually practised by teenage girls and young women, and it may be growing more common as the secret is exchanged on Internet bulletin boards for diabetics and those with eating disorders.

Risking coma and early death
One expert who has studied the phenomenon estimates that 450 000 Type 1 diabetic women in the United States - one-third of the total - have skipped or short-changed their insulin to lose weight and are risking coma and early death.

"People who do this behaviour wind up with severe diabetic complications much earlier," said Ann Goebel-Fabbri, a clinical psychologist at the Joslin Diabetes Centre in Boston.

The American Diabetes Association has long known about insulin omission as a way to lose weight. But "diabulimia" is a term that has only cropped up in recent years and is not a recognized medical condition, said Barbara Anderson, a paediatrics professor at Baylor College of Medicine in Houston.

Type 1 diabetes is a disorder in which the body's immune system attacks insulin-producing cells in the pancreas. People with this disease produce little or no insulin, so they take shots of the hormone daily.

It differs from Type 2, the form associated with obesity and which accounts for about 90 to 95 percent of all diabetes.

Insulin is vital for delivering glucose from the bloodstream to the body's cells. Without insulin, cells starve even while the bloodstream becomes burdened with too much glucose.

When Type 1 diabetics skip or reduce their insulin, they risk falling into a coma or even dying. Blindness, amputations and kidney failure are some of the possible long-term complications.

The warning signs
Warning signs for diabulimia include a change in eating habits – typically someone who eats more but still loses weight – low energy and high blood-sugar levels, Goebel-Fabbri said. Frequent urination is another signal. When sugars are high, the kidneys work overtime to filter the excess glucose from the blood.

This purging of sugar from the body through the kidneys is similar to someone with bulimia, who binges and then purges, or vomits, Anderson said.

Studies suggest that women with Type 1 diabetes are twice as likely to develop an eating disorder. Ironically, good diabetes management, which requires a preoccupation with food, counting carbohydrates and following a diet, may lead some diabetics to form an unhealthy association with food, Goebel-Fabbri said.

Jacq Allan, 26, is a diabulimic. She said she had not taken her insulin shots for two weeks and rarely takes them regularly. She weighs 19 kilograms less than she did a year ago.

Stuck between two fears
Allan is stuck between two fears: taking insulin, which may lead to weight gain, and the damage her destructive compulsion is doing to her body.

"I'm terrified of insulin," Allan said. "Every morning I wake up and think maybe I should go to the hospital." Diagnosed with Type 1 diabetes nearly three years ago, Allan said she can feel the constant, sky-high sugar in her blood. Her list of ailments - chest pain, heart palpitations, muscle cramps, bacterial infections and lower back pain - are not the usual health problems of a twenty-something.

"I'm constantly worried that my eyes are going to go, but they seem relatively OK for the moment," she said. "I always wonder if this will be the day that some major organ fails. I kind of want something to happen because then maybe I'll stop." – (Sapa-AP)

Read more:
Diabetes Centre
Eating disorders

June 2007


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Dr. May currently works as a fulltime endocrinologist and has been in private practice since 2004. He has a variety of interests, predominantly obesity and diabetes, but also sees patients with osteoporosis, thyroid disorders, men's health disorders, pituitary and adrenal disorders, polycystic ovaries, and disorders of growth. He is a leading member of several obesity and diabetes societies and runs a trial centre for new drugs.

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