Posted by: | 2019/04/12


Replacement for GLP-1 drugs

My nephro took me off Trulicity late last year because my creatinine was at 2.0. This drug had kept my A1C at no higher than 7.0 for about three years in addition to about 40 units of Glargine twice daily and Humalog (used rarely). Consequently, my glucose control had deteriorated to about 9.0 despite using about 50 units of glargine and Humalog almost every night as needed. After I embarked upon a much stricter diet than before, my glucose levels are moving in the right direction but are far from being as good as with Trulicity. Can you tell me if there's any drug outside of the GLP-1 family that is not harmful for the kidneys, which can be used in place of such medications.

Expert's Reply


Diabetes expert
- 2019/04/15


There are no other injectable options besides for insulin. In terms of tablets, you could try one of the DPP4 inhibitors like Galvus, Januvia or onglyza

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