Glucophage has been used to try and delay the onset of diabetes, but isn't used first line, as lifestyle changes should be made first, and then glucophage would be used if this fails, i.e glucose levels continue to rise. Type 2 diabetes can be prevented or delayed, and trials done in high
risk patients have shown that by losing 4 kg's in 4 years, one can reduce their
chances of getting diabetes by 58%. Most trials used a low fat, high fiber, low
GI diet with exercise, but potentially a low carb diet would work as well.
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