Updated 04 July 2014

Gene predicts responsiveness to anti-depressants

Researchers at Tel Aviv University have discovered a gene that may reveal whether people are likely to respond well to SSRI anti-depressants.

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed anti-depressants, but they don't work for everyone.

Sackler faculty members Prof. Moshe Rehavi of the Department of Physiology and Pharmacology and Dr Metsada Pasmnik-Chor of the Bioinformatics Unit were co-authors of the study, published in Translational Psychology.

The TAU researchers are working to confirm their findings on the molecular level and with animal models. Adva Hadar, a master's student in Dr Gurwitz's lab, is using the same approach to find biomarkers for the personalized treatment of Alzheimer's disease.


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