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Depression

25 August 2011

Antidepressant tied to heart risk

High doses of the popular antidepressant Celexa (Cipramil in SA) can cause potentially fatal abnormal heart rhythms and should no longer be prescribed to patients, the FDA has said.

High doses of the popular antidepressant Celexa (known as Cipramil in South Africa) can cause potentially fatal abnormal heart rhythms and should no longer be prescribed to patients, the US Food and Drug Administration has said.

Even though studies have not found that doses higher than 40 mg a day offer any benefits to patients with depression, Celexa's drug labelling previously stated that some patients may require a dose of 60 mg a day, the agency noted.

The label has been revised to include the new dosage limit as well as information about the potential for abnormal heart electrical activity and rhythms.

 

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