We need to consider a number of alternatives. Major Depressive Disorder is common, so it's often a possibility. But then you say she has recently lost her daughter and granddaughter, so surely she is grieving about these sad losses, and bereavement can look very like depression. Then you say that she has recently found out that she is HIV positive : which would be upsetting for anyone. So a very real possibility is that she is, just as unpleasantly for her, severely sad and anxious about all of these things.
But then I think : you began by saying that she is taking "mental illness medication", which surely means that she has already, a while ago, seen a doctor or psychiatrist with symptoms, and some diagnosis was made, and treatment was started. You haven't told me who she saw or what the diagnosis was, or what the medicines are.
I think, especially because the situation is complicated, it would surely be best for her to see the same doctor she saw before, who will have the essential knowledge of how she was before, what diagnosis was made, and what that treatment is, which is needed to properly assess her present situation, and what different or further treatment may be needed.
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