Posted by: Marie | 2019/07/24


Is EXSIRA safe during pregnancy

I have been on EXIRA 100mg for the past 5 years, I am 6 months pregnant and still using it. I have not found any research indicating its safety during pregnancy. I stopped it and have been having anxiety/panic attacks. I am uncertain as to how and whether I should continue, till I deliver. It is extremely difficult to continue without it, however I am also aware that it could pose possible harm/danger to my unborn child. I tried to access the register of antidepressants safe to use during pregnancy, however it is in America. Your assistance /response is highly appreciated.

Expert's Reply


Depression expert
- 2019/07/24

Hi Marie,
Thanks for your sensible and important question.  Exsira is the antidepressant Desvenlafaxine.  I'm not sure whether you stopped it abruptly ( not a good idea ) or gradually, with your doctor's advice ; but there can be withdrawal symptoms with most of these drugs if they are stopped suddenly.
It is generally considered one of the safer AD's to take during pregnancy, compared with some others, but it's best to discuss this with your doctor, who should know the details of your condition.  One has to consider the risk of a return of the depression / anxiety /panic and that potential impact on pregnancy, with the possible risk of the drugs.  This drug has shown little risk to the baby ; some concerns about uncommon risks to the mother if taken very late in pregnancy.  Research to get more certain information on these issues is hard to do or to get paid for.  So have a chat with your prescribing doctor

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