Posted by: Audry | 2019/01/11


Can you take purata, Cilift and dopaquel together and which one what time of the day.

My mom has been severely depressed and anxious for the last 5 month's and first GP prescribed Nuzak and Dopaquel. She had severe side effects on the Nuzak and my GP changed it to Cilift 20mg once a day. She's been on purata for years and dr said she must stay on it. She takes 15mg in the morning and 30mg at night. It's to help with anxiety and sleeping. She's only been on Cilift for 5 days now and I can see a slight improvement but she still gets very anxious. She hasn't started the Dopaquel yet, too scared to take all tablets together. She's 78 years old. Can she take all three together and at what time of the day.?

Expert's Reply


Depression expert
- 2019/01/21

Hello Audry,
My policy is that when treatment get complicated, and the usual treatment is not working well, and especially with an older patient, they should  be seen and assessed by a specialist psychiatrist, to confirm diagnosis and treatment plan. Dopaquel isn't a drug I would usually expect to be prescribed by a GP except on the advice of a specialist, for instance .
Purata is a trade name for Oxazepam, one of the benzodiazepine sedative tranquillizers. Nowadays, because there is a risk of possible dependency, specialists and experts tend to advise that it should be use for only 2 months.  But it is very important with any such drug affecting the brain, NOT to stop it suddenly, but only gradually and on the advice of a doctor.
Any doctor would not prescribe 3 drugs to be taken together unless he was satisfied that the combination was safe. 
In older people, one also needs to be aware of whether any drugs might cause drowsiness, balance problems, etc., as falls can be more possible and serious at age.
Cilift is a popular antidepressant which can be rally useful in depression AND anxiety. 
Overall, I'd suggest considering arranging a second opinion from a specialist psychiatrist,

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