The widely used cancer drug bevacizumab (Avastin) is associated with a more than fourfold increased risk of severe urinary protein loss, a new review finds.
In the review, 2.2% of the patients taking Avastin experienced severe proteinura, with patients who were taking the highest doses of the drug facing an even higher risk. Also, the type of cancer played a role in the risk of kidney trouble, with kidney cancer patients seeing the greatest risk (10.2%).
Avastin recently approved
Kidney cancer is the eighth most commonly diagnosed cancer in the United States. The cancer society estimates that there will be about 57 760 new cases of kidney cancer in the United States this year, and about 12,980 people will die from the disease. - (HealthDay News, June 2010)