belongs to a family of medicines used to treat cancer called the vinca-alkaloid
family. Navelbine is used to treat:
cell lung cancer
breast cancer that has not responded to other medicines.
is not recommended for use by children under 18 years old.
not take Navelbine soft capsule
If you are allergic (hypersensitive) to the active ingredient, vinorelbine, or
any of the related family of cancer drugs called the vinca alkaloids.
If you are allergic to any of the other ingredients in Navelbine capsules
(refer to section 6 of this leaflet).
If you are pregnant or think that you might be pregnant.
If you are breast feeding.
If you have a severe liver disease.
If you have had an operation on your stomach or small bowel, or if you have gut
disorder which affects how you absorb food. These may affect how your body
If you have a low white blood cell count (neutrophils, leucocytes) or a severe
infection current or recent within two weeks.
If you have a low blood platelet cell count (thrombocytopenia).
If you plan to have a yellow fever vaccination or have just had one.
If you require long-term oxygen therapy
in doubt, ask your doctor or pharmacist.
special care with Navelbine soft capsule
inform your doctor if:
- You have a history of heart attack or severe
chest pain. - Your ability to carry out activities of daily living is strongly
You have problems with your liver or you have received radiotherapy where the
treatment field included the liver.
If you have been told by your doctor that you have an intolerance to some
sugars, contact your doctor before taking this medicinal product.
You have symptoms of infection (such as fever, chills, joint pain, cough).
You take, or have recently taken, any other medicines including medicines
obtained without a prescription.
You plan to have a vaccination or have just had one Before and during your
treatment with Navelbine blood cell counts are performed to check that it is
safe for you to receive treatment. If the results of this analysis are not
satisfactory, your treatment may be delayed and further checks made until these
values return to normal.
inform your doctor or pharmacist if you are taking, or have recently taken, any
other medicines, including medicines obtained without a prescription.
you are given Navelbine as well as medicines that affect your bone marrow it
may make some of the side effects worse.
doctor should take special attention if you are taking the following medicines:
medicines used to thin your blood (anticoagulants),
an anti-epileptic medicine called phenytoin,
antifungal medicines such as itraconazole and ketoconazole,
an anti-cancer medicine called mitomycin C,
medicines that impair your immune system such as ciclosporin and tacrolimus
vaccines (live attenuated vaccines) are not recommended during treatment.
being treated with Navelbine are advised not to father a child during and up to
3 months after the last capsule. You should discuss sperm banking with your
doctor before starting treatment with Navelbine.
of child bearing age Women of child-bearing age must use effective
contraception (birth control) during treatment and up to 3 months after
not take Navelbine if you are pregnant, or think that you might be pregnant. If
you have to start treatment with Navelbine and you are pregnant, or if
pregnancy occurs during your treatment with UK Navelbine