Posted by: | 2018/06/11


hi can i have some comment on Nevalbine. is it safe and effective?

my wife has bone metastasis

Expert's Reply


Cancer expert
- 2018/06/11

Dear Anonymous:

Navelbine belongs to a family of medicines used to treat cancer called the vinca-alkaloid family. Navelbine is used to treat:

Non-small cell lung cancer

Advanced breast cancer that has not responded to other medicines.

It is not recommended for use by children under 18 years old.


Do not take Navelbine soft capsule

• If you are allergic (hypersensitive) to the active ingredient, vinorelbine, or any of the related family of cancer drugs called the vinca alkaloids.

• If you are allergic to any of the other ingredients in Navelbine capsules (refer to section 6 of this leaflet).

• If you are pregnant or think that you might be pregnant.

• If you are breast feeding.

• If you have a severe liver disease.

• If you have had an operation on your stomach or small bowel, or if you have gut disorder which affects how you absorb food. These may affect how your body absorbs Navelbine.

• If you have a low white blood cell count (neutrophils, leucocytes) or a severe infection current or recent within two weeks.

• If you have a low blood platelet cell count (thrombocytopenia).

• If you plan to have a yellow fever vaccination or have just had one.

• If you require long-term oxygen therapy

If in doubt, ask your doctor or pharmacist.


Take special care with Navelbine soft capsule

Please inform your doctor if:

 - You have a history of heart attack or severe chest pain. - Your ability to carry out activities of daily living is strongly reduced.

- You have problems with your liver or you have received radiotherapy where the treatment field included the liver.

- If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

- You have symptoms of infection (such as fever, chills, joint pain, cough).

- You take, or have recently taken, any other medicines including medicines obtained without a prescription.

- You plan to have a vaccination or have just had one Before and during your treatment with Navelbine blood cell counts are performed to check that it is safe for you to receive treatment. If the results of this analysis are not satisfactory, your treatment may be delayed and further checks made until these values return to normal.


Taking other medicines

Please inform your doctor or pharmacist if you are taking, or have recently taken, any other medicines, including medicines obtained without a prescription.

If you are given Navelbine as well as medicines that affect your bone marrow it may make some of the side effects worse.


Your doctor should take special attention if you are taking the following medicines:

- medicines used to thin your blood (anticoagulants),

- an anti-epileptic medicine called phenytoin,

- antifungal medicines such as itraconazole and ketoconazole,

- an anti-cancer medicine called mitomycin C,

- medicines that impair your immune system such as ciclosporin and tacrolimus

Many vaccines (live attenuated vaccines) are not recommended during treatment.


Male fertility

Men being treated with Navelbine are advised not to father a child during and up to 3 months after the last capsule. You should discuss sperm banking with your doctor before starting treatment with Navelbine.


Women of child bearing age Women of child-bearing age must use effective contraception (birth control) during treatment and up to 3 months after treatment.



Do not take Navelbine if you are pregnant, or think that you might be pregnant. If you have to start treatment with Navelbine and you are pregnant, or if pregnancy occurs during your treatment with UK Navelbine


The information provided does not constitute a diagnosis of your condition. You should consult a medical practitioner or other appropriate health care professional for a physical exmanication, diagnosis and formal advice. Health24 and the expert accept no responsibility or liability for any damage or personal harm you may suffer resulting from making use of this content.

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