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22 September 2010

Researchers Identify Markers for Aplastic Anemia Risk

Shorter 'caps' on chromosomes prior to treatment predict higher odds of relapse, death, researchers find

This article has not necessarily been edited by Health24.

This study included 183 patients with severe aplastic anemia who underwent immunosuppressive therapy between 2000 and 2008. The researchers examined changes in the length of the patients' telomeres, which are cap-like structures at the end of chromosomes that protect those ends from deterioration. Telomeres naturally shorten as people age, but their length can also be shortened by genetic factors or environmental stressors.

 
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