advertisement
20 July 2010

Better Way to Predict Success of Second IVF Attempt?

Data gleaned from first try can help gauge odds of pregnancy the next time, researchers say

0

This article has not necessarily been edited by Health24.

MONDAY, July 19 (HealthDay News) -- A new technique could give women a better idea of whether they're likely to become pregnant in a second attempt at in-vitro fertilization (IVF) after failing a first time.

In a new study, researchers from the Stanford University School of Medicine report that their method -- which relies on data gleaned from the first IVF cycle -- is 1,000 times more accurate than the age-based guidelines currently used to predict the success of a second IVF cycle.

Age-based predictions often confuse women seeking a second chance at pregnancy. "Many patients, even if they have insurance coverage, will drop out -- either because they don't understand what their odds are, or they find it's a very emotionally challenging experience to go through," study co-author Dr. Lynn Westphal, an associate professor of obstetrics and gynecology, said in a university news release.

In the new study, published online July 19 in the Proceedings of the National Academy of Sciences, researchers examined records of 1,676 in-vitro fertilization cycles at Stanford Hospital & Clinics from 2003 to 2006.

They came up with 52 factors, including hormone levels and quality of eggs, that affect the outcome of a second IVF attempt and used a computer program to determine how those factors interact. Then they used their findings to predict the outcome of more than 600 treatments from 2007 to 2008.

About 60 percent of the time, their predictions differed from the predictions based purely on age.

"For some of the patients, we may be able to reassure them and help them move forward and do another cycle if they have good odds," Westphal said in the release. "For other patients, if they're in a poor category, we'll help them move on to consider better options."

Stanford holds the patent on the test, and two researchers have formed a company to develop the tests.

Obstetrician Dr. Laurel Stadtmauer, said the study relies on "sound and sophisticated" statistical analysis and confirms that age isn't the only factor affecting the success of second fertilization attempts."

Turning the results into a grade or number that could be given to patients would be helpful, added Stadtmauer, an associate professor of obstetrics and gynecology at Jones Institute for Reproductive Medicine in Norfolk, Va.

More information

For more about infertility, visit the U.S. National Library of Medicine.


(Copyright © 2010 HealthDay. All rights reserved.)

 
NEXT ON HEALTH24X
advertisement

Read Health24’s Comments Policy

Comment on this story
0 comments
Comments have been closed for this article.

Live healthier

Contraceptives and you »

Scientists create new contraceptive from seaweed Poor long-term birth control training leads to 'accidents'

7 birth control myths you should stop believing

Will the Pill make you gain weight? Can you fall pregnant while breastfeeding? We bust seven common myths about birth control.

Your digestive health »

Causes of digestive disorders 9 habits that could hurt your digestive system

Your tummy rumblings might help diagnose bowel disorder

With the assistance of an 'acoustic belt', doctors can now determine the cause of your tummy troubles.