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Allergy

Question
Posted by: | 2020/03/18

Q.

How to wean off high dosages of antihistamines in management of chronic urticaria

Hello I have chronic urticaria for the last 2.5 months and only managed to get it under control for the last week by adding cimetidine 400mg at night (i mainly get them at night). My current treatment regime is as follows: 2 x fexo 180mg in the morning 2 x xyzal/levocetirizine at night 1 x cimetidine 400mg at night 1 x montelukast 10 mg at night I would appreciate any advise on how to wean myself off these high dosages as it is super costly here and the meds always make me super drowsy as well. Is it just trial an error? I am planning to slowly remove for example montelukast this Friday and see the results on Saturday. Then I would like to try swopping fexo for another antihistamine as fexo is the most expensive. Thank you. I look forward to hearing from you

Expert's Reply

A.

Allergy expert
- 2020/04/03

Dear I. You are obviously struggling with your urticaria judging by the number of posts you place on this website. Chronic Urticaria can persist for years (you have had it 2.5 months). Ask your GP to prescribe a short course oral prednisone, but keep taking the high dosages of antihistamine. Cimetidine and Montelukast are probably ineffective and your doctor could consider stopping them.

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