A lack of leptin contributes to the absence of menstrual periods in women with extremely low levels of body fat, but treatment with a synthetic form of the hormone may restore both the menstrual cycle and fertility, a new study indicates.
The randomised, double-blind study included 20 women, ages 18 to 35, with HA. Many of them were runners. Over 36 weeks, the women received daily injections of either a synthetic form of leptin called metreleptin or a placebo, without the participants or the researchers being aware who was receiving the real or sham therapy.
Hormones and periods