04 September 2009


Cocaine is a naturally derived CNS (central nervous system) stimulant extracted and refined from the coca plant.

Original article by

Cocaine is a naturally derived CNS (central nervous system) stimulant extracted and refined from the coca plant grown primarily in the Andean region of South America. Cocaine is typically a whitish powder with a bitter, numbing taste. It is most often insufflated (snorted), though it can also be injected and used orally.

While powder cocaine can be smoked to some effect (despite common belief otherwise), it is a very inefficient method of ingestion. Because of the high temperatures present when smoking, powder cocaine tends to burn rather than vaporise. For this reason, freebase cocaine, also known as crack in its street form, is created from powder cocaine for smoking. Freebase cocaine vaporises at smoking temperatures providing more effect with less material, as well as faster onset and a more intense high than powder cocaine.

The chemical name for cocaine is benzoylmethyl ecgonine (C17H21NO4). It is a bitter, white, odourless, crystalline drug.

Coca leaf chewing has been practiced for thousands of years. Cocaine was first isolated from the Erythroxylon coca plant around 1850. Medicinal use of cocaine increased through the late 19th century and recreational use started to become a known problem in the early 20th century. Recreational use was banned in the United States in 1914.

The Substance: Cocaine: Coke; Snow; Nose Candy; Dust; White Lady; Toot; Llello.
Freebase Cocaine: Crack; Rock.
The Experience: Coked up.

As with many substances, the effects of cocaine depend greatly on the person and the dose. Possible effects include feelings of well-being, decreased appetite, stimulation, sexual arousal, and increased focus. Negative effects can include increased body temperature and heart rate, agitation and anxiety, paranoia, dizziness, nausea/vomiting, violent behaviour, kidney failure, seizure, stroke, and heart attack.

Onset varies depending on method of ingestion. Snorting cocaine will produce effects within a minute. Smoking freebase cocaine produces effects almost immediately - often before exhaling. Injected cocaine also produces effects within a few seconds.

The effects of snorted cocaine are quite short with the primary high lasting only 20-40 minutes. This is one of the reasons leading to problems with addiction. As the effects wear off, more is often snorted. This pattern of repeated use can quickly move in the direction of addiction. A hit of smoked crack (freebase cocaine) will typically produce effects lasting five to 15 minutes.

Street cocaine is quite often impure. The more direct the route of administration, the more dangerous this can be. Injecting impure cocaine can be deadly. Repeated snorting can cause severe damage to the nose. Smoking of freebase cocaine can cause breathing difficulties.

Research shows that cocaine use during pregnancy may increase chances of miscarriage, premature labour, and stillbirth. Cocaine is likely to be passed to a child during breastfeeding, resulting in irritability and lack of appetite in the baby.

Addiction potential
One of the most problematic aspects of cocaine is its addictive qualities. While cocaine is not believed to be physically addictive, it is, without a doubt, psychologically addictive. Those who use cocaine heavily or regularly frequently encounter great difficulty ceasing use.

Many people find themselves drawn to overusing both crack and powder cocaine. Initial tolerance develops rapidly, especially with heavy use, though tolerance appears to level off relatively quickly (users do not generally require more and more material over time, once they have reached heavy use).

- Article used with the permission of Last modified April 2009.

Erowid caution and disclaimer

This Erowid article is a summary of data gathered from Erowid site visitors, government documents, books, websites, and other resources. As this field is complex and constantly changing, information should always be verified through additional sources.


Read Health24’s Comments Policy

Comment on this story
Comments have been closed for this article.

Live healthier

Lifestyle »

E-cigarettes: Here are five things to know

E-cigarettes have become hugely popular in the past decade, but a rash of vaping-linked deaths and illnesses in the US is feeding caution about a product that's already banned in some places.

Allergy »

Ditch the itch: Researchers find new drug to fight hives

A new drug works by targeting an immune system antibody called immunoglobulin E, which is responsible for the allergic reaction that causes hives.