activity may reduce the risk of oesophageal cancer, a new review finds.
Researchers analysed four
published observational studies, and found that the most physically active
people were 19% less likely to develop oesophageal cancer than those who were
The review also found that
people who were physically active had a 32% lower risk of developing a type of
cancer called oesophageal adenocarcinoma, which can arise from a condition
called Barrett's oesophagus.
The findings are scheduled
for presentation at the American College of Gastroenterology annual
meeting, in San Diego.
"Obesity has been
associated with increased risk of oesophageal cancer through high levels of
insulin, as well as chronic inflammation," study author Dr Siddharth
Singh, of the Mayo Clinic in Rochester, Minnesota, said in a college news release.
visceral fat, lowering the level of carcinogenic adipokines, improving insulin
sensitivity and decreasing chronic inflammation, physical activity can
potentially decrease the risk of oesophageal cancer," Singh said.
Too early to
It's too early to conclude
that exercise directly decreases oesophageal cancer risk, said Singh, who noted
that physically active people may be more likely to have healthy lifestyles
than those who aren't physically active. It also may be possible that healthy
habits other than physical activity could contribute to the lower risk of oesophageal
Oesophageal cancer is the
sixth most common cancer in men worldwide, and the five-year survival rate is
about 15%, with most patients dying within the first year after diagnosis.
Research presented at
medical meetings should be viewed as preliminary until published in a
The US National Cancer
Institute has more about oesophageal