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Question
Posted by: B | 2004/02/09

Trepiline treatment for Migraine

I am presently taking 5 x 25mg Trepiline daily.When I attempt to lower the dosage, the frequency of Migraine increases dramatically.At this high dosage I am getting recurring bladder infections.Is there anything else similar to Trepiline which does not present the urine retention side effect of Trepiline.
Many thanks
B

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Our expert says:
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B, migraine prophylaxis is a tricky thing. There is no treatment that is guaranteed to work. The important thing about migraine is to try and prevent the thing from happening. Try to identify the triggering factors (see above) which cause your migraine, by studying the pattern of events before an attack. By keeping a dairy in which you note changes in routine, food and drink etc. and eliminating the triggering factor, you can prevent a migraine attack or at least eliminate the need for prophylactic treatment. Try to eat regular meals, as low blood sugar can also trigger an attack. If you don’t have the time, drink a Coca-Cola (wonderful stuff, tastes great and has medicinal value). If you suffer from two or more attacks per month, your friendly neighbourhood GP should prescribe a preventative medicine to be taken daily for a period of time. Methysergide (Deseril®) is effective but can cause eye, lung and heart damage if taken for longer than three months. Clonidine (Dixarit®) and Pizotifen (Sandomigran®) have also been used with success. All three of them are not safe to be taken during pregnancy and breast feeding. Propranolol 20 to 40mg, 3 to 4 times a day, offers long-term relief in half of patients. Unfortunately the whole prophylaxis thing is a matter or trial and error. This applies to the elimination of trigger factors as well as the prophylactic drug of choice. The good news though, is that migraine is not dangerous, just very unpleasant. You just have to be sure that it is migraine, otherwise a visit to your friendly neighbourhood GP should be on the cards.
The trigger factors have been identified include the following:
 Certain foods, especially coffee, chocolate, nuts, dairy products, red wine, fried foods, shellfish, citrus fruits, spicy foods, cured or processed meats, peanuts and yeast.
 Emotional and physical stress. This includes anger, anxiety, depression, and excitement.
 Lack or excess of sleep.
 Missed meals.
 Loud noises.
 Bright or flashing lights.
 Alcohol.
 Oral contraceptives.
 Menstruation.
Good luck and let me know if you have more questions (just post them as a new question to ensure that I get them).

The information provided does not constitute a diagnosis of your condition. You should consult a medical practitioner or other appropriate health care professional for a physical exmanication, diagnosis and formal advice. Health24 and the expert accept no responsibility or liability for any damage or personal harm you may suffer resulting from making use of this content.

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Our users say:
Posted by: Patty | 2004/11/22

I has been put on Trepiline and 1 dosage of 25mg have put me to sleep for 18 hours. I hardly can believe the previous patient could take 5 x 25mg a day.... Do you think I am allergic

Reply to Patty

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