Our expert says:
All you can do is what you have done - provide advice and support. There are so many aspects of this which are ultimately your niece's responsibility. You have warned her about the risks, and if she chooses not to listen, she will have to face the consequences.
If you feel that she is seriously out of control then you need to have her assessed for treatment posibly on an in-patient level. She is still a minor and if she is going to go out without permission you should consider involving the police and social services child protection.
There is no magic solution to getting through to someone - helping them to reflect on their mistakes may be all you can do at this stage to help her make different decisions for herself.
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