Our expert says:
Hello again ...,
Seroquel is relatively new, but has been around for some years now. As you know, numerous of the drugs that are found to be effective in Bipolar Disorder in terms of stabilizing the swings, tend to be drugs originallty developed for epilepsy ( which condition also needs stabilization of chemical interactions across nerve cell membranes ) ; and many of those used in manic phases are drugs originally developed for use in schizophrenia, where the efects of calming without too much sedation, and helping to clarify one's thinking, are also needed.
I haven't used Seroquel lately, but liked the look of the evidence on it when it was released and since, and have heard good things of it.
Remember, too, that the effect of sedatives can be interesting when someone is high, and they are usually less sedated by it than any of the rest of us would be --- though when the high ends, they may again become sensitive to being more sedated by it.
Delene's experience is curious, as I have never heard of anyone using Seroquel to help people sleep --- and when a drug like that which is designed for more regular use over months, is taken only at night, there's never time for your system to get used to it and sedative side-effects.
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