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One of the problems with some viruses, AIDS and Flu, though not related, sharing this characteristic, is that they keep mutating and changing, so even if we develop immunity to one version, that may not work against another version --- which is why they need to manufacture a new type of flu vaccine every year, based on whatever new flu strain is prevalent this time round. These viruses are a bit like a Rubik's Cube, if you can remember that old toy. In a way it's wlays a cube, but just a flick of the fingers, and the outer pattern has changed again.
And yes, very definitely, several types of virus, and Flu is an especially bad culprit in this regard, can drain one and cause or worsen a Depression, something which is well-established in research and experience.
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