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Question
Posted by: Pam | 2007/07/19

Pre testing embryo - PGD

Is this a standard test in IVF/ICSI or do you have to request the test? What does it involve?

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Our expert says:
Expert ImageFertility expert

Dear Pam

The Pre-Genetic diagnostic test (PGD) is a test which involves removing a single cell from within an embryo and having this cell analysed. One would need to know beforehand precisely what one intends to test for since there are various chromosomal anomalies or chromosomal defects requiring specific probes. Also, in the case of single gene defects specific protocols need to be followed. Although the test is relatively safe with respect to the embryo the results are not always 100% accurate due to the possibility of mosaicism. This occurs when there are two different genetic cell lines within one embryo and therefore the single cell tested may not be fully representative of the entire embryo. Furthermore the cost of this process is formidable and you would need to discuss this in more detail with the fertility specialist.

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