Our expert says:
Dear Please help
Unfortunately, in general if the testis biopsy does not detect any sperm the outlook or prognosis is extremely poor. However, the fact that some sperm or be it a very low count was detected a year ago may suggest that the testicular failure is of fairly recent onset. Therefore I would perhaps consider the use of FSH suppressing agents such as zoladex or even lucrin and maintain the suppression for at least one and a half to two months. This can then be followed up with a form of testicular stimulation and a repeat testis biopsy can be done a month or two later or even a routine sperm analysis can be done shortly thereafter. It would be extremely important that the specimen be analysed by a laboratory capable of dealing with fertility issues so as to freeze the specimen immediately if either sperm or precursors of sperm are noted. It is possible to mature sperm precursors in a laboratory environment and these can then be used for ICSI procedures.
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