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Question
Posted by: meds | 2007/04/03

medications for depression in pregnancy

hi
I am being told different things by 3 different doctors, maybe you can help.
i take a combination each day of lamictin50mg, wellbutrin 1 tablet and cipramil20mg for bipolar depression. are these ok to take while trying to fall pregnant and while being pregnant? what would the side effects be?
i dont think i can take the chance of not being on them for even a short period.
also, what aboutr lipitor10mg for cholestrol?
thanks!

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Our expert says:
Expert ImageGynaeDoc

Here is some information fegarding your medications:
Lamictin : Has been associated with various congenital abnormalities, including a fetal syndrome chiefly comprising facial deformities. The risk of teratogenesis is not known accurately but spina bifida is estimated to occur in 1-2% of first trimester exposures. The risk-benefit ratio must be carefully considered as well as the danger of changing therapy during pregnancy. Category D. ( SA Medical Formulary)
Wellbutrin : One study showed no greater risk for congenial malformations overall, or cardiovascular malformations specifically, following first trimester bupropion exposure compared to exposure to all other antidepressants in the first trimester, or bupropion outside of the first trimester. The results of this study have not been corroborated. WELLBUTRIN XL should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as animal stydies have shown evidence of harm.
Cipramil : The SSRI which has been tested the most ios Prozac, which is relatively safe. One may assume the same about Cipramil.
Lipitor is contraindicated in pregnancy.

Best wishes

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