Our expert says:
Mick, there are still some options available to you including drugs like Uprima® (apomorphine), repairing the defect and of course a penile prosthesis
· Another oral drug called Vasomax (phentolamine) is still being tested, but it does not seem to have the effectiveness of Viagra with a 40% response in men tested. At higher doses, a lowering of blood pressure may be problematic.
· All of the oral drugs have different modes of action and if one does not work, the others may. Combinations of drugs, (e.g. Viagra and ?) and other techniques may also be possible.
· In recent European studies, a new injectable drug called VIP is being tested. VIP stands for vasoactive intestinal peptide. When mixed with phentolomine (Regitine), an older injectable drug, 80% of men had successful erections, even if they had failed other injectables. Studies are underway in the US.
· Two other injectables being researched abroad are called moxislyte and forskolin Initial success rates of 80% are being reported. No US studies are yet completed.
· North American studies of creams containing nitroglycerin that are applied to the penis have shown modest success in mild to moderate erectile dysfunction. Plans to study this drug in the US are planned.
· South American studies of creams containing prostaglandin (Alprox-TD) that are applied to the penis have shown modest success in mild to moderate erectile dysfunction. No plans to study this drug are planned in the US for now.
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