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Question
Posted by: Hilary | 2007/04/23

Elevated FSH and Injectables


Dear Doctor

Thank you very much for your very complete and explanatory answes to the various questions. i really enjoy reading them- its always "different" in that it is patient-specific instead of just generalisations.

However, I have had this burning question for a long time, but have not seen anyone ask it yet. I know that you will be able to give me a more than satisfactyory answer"

I would like to know why do fertility experts still recommend injectables such as Gonal F and the like injectables even though a patients FSH is already high?
Would'nt this increase FSH further and thus lead to poorer egg quality?

I was always confused about this and am confident that you will ultimately put my case to rest>

Thanks once again for an excellent forum.

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Our expert says:
Expert ImageFertility expert

Dear Hilary

In the first instance the reasons for the naturally elevated FSH level is a compensatory mechanism by the pituitary gland to override the ovarian resistance or poor ovarian response. Such elevation of FSH is often seen in peri-menopausal women and is the bodies attempt to continue maintaining ovulation despite the poor reserves within the ovary.

In cases pertaining to fertility the objective of a high dose FSH is to assist the pituitary gland in overcoming the ovarian resistance and hence to force follicle production and hopefully ovulation. In my practice I often use an antagonist to first suppress FSH production, which will then allow ovarian receptors to recruit and be more sensitive when we attempt high dose injectables.

The information provided does not constitute a diagnosis of your condition. You should consult a medical practitioner or other appropriate health care professional for a physical exmanication, diagnosis and formal advice. Health24 and the expert accept no responsibility or liability for any damage or personal harm you may suffer resulting from making use of this content.

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