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Question
Posted by: Book Worm | 2007/05/12

DNA testing

I enjoy reading science articles and cant really figure certain things out.
Taking paternity testing as an example using methots currently at you disposal, how reliable is DNA testing in terms of accuracy,Has there ever been falsely reported cases and how was it picked up?(in any type of case e.g crime, paternity etc.)And how do you "exclude" mutation of genes in your testing proses.

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Our expert says:
Expert ImageGeneticist

Dear Book worm

DNA testing is very accurate and inclusion or exclusion of paternity is based on a statistical calculation. It looks at the chance that the genetic variation would occur in the child vs alleged father in relation to its frequency in the general population, which may also differ between different ethnic groups. There has been falsely reported cases and it is usually picked up when the test is redone with another method that use an alternative set of markers. The possibility of a new mutation that can affect the results cannot be excluded but this is why many different markets are used to minimise the effect it may have on the outcome of the test.

Regards, Maritha

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