Our expert says:
It's unlikely - the caffeine content of a cup of coffee is pretty low, certainly by comparison with what is studied in research trials on it. So the application of research presents problems, because the amounts are so different. My gut feel is that the impact is likely very small, probably negligible. Of course, if you could find an alternative flavouring agent, you'd be better off in terms of not having a potential downside to think about. But right now, I honestly don't think it's a major consideration.
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