Posted by: UF | 2008/06/12

CA125 tumor indicator

A pelvic ultrasound has revealed an enlarged uterus and the presence of multiple uterine fibroids ( two in approx 7cm diameter plus 1 of approx 2cm impinging on bladder)

My question Is: is an elevated CA125 count of 154 possibility indicative of Endometrial cancer? Or is it the uterin fibroids giving rise to this elevated count? Should a hysteroscopy be conducted on the basis of this count ?
What treatment would you recommend for the fiborids given that there is no undue heavy bleeding - only pressure on bladder, resulting in increased frequency of urination? Please advise

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Our expert says:
Expert ImageCyberDoc

Hallo UF
CA125 is a screening test for uterine cancer but can also be increased in inflammatory conditions of the pelvis, diseases of the ovaries or endometriosis. The decision to do a hysteroscopy would depend on the overall gyne examination, the sonar results, and whether the gyne wants to do a biopsy of the fibroid to ensure that it is not cancerous. If there is pressure on the bladder they usually will want to remove either the fibroid or do a hysterectomy if a patient does not want to have any more children or if the tumour is cancerous.
Dr Bets

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Our users say:
Posted by: UF | 2008/06/13

Thanks for the response.

Are there any other reliable and less invasive options for removing uterine fibroids apart from a full hysterectomy?

Reply to UF

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